|Immunohistochemistry (Paraffin) (IHC (P))||5 - 8 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from C-terminus of human OPN3 / Encephalopsin.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset (94%) Panda (81%).
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. May play a role in encephalic photoreception. Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ECPN; Encephalopsin; ERO; NMO-1; OPN3; Opsin 3; opsin 3 (encephalopsin, panopsin); Opsin-3; Panopsin; protein phosphatase 1, regulatory subunit 116
Gene Aliases: ECPN; OPN3; PPP1R116
UniProt ID: (Human) Q9H1Y3
Entrez Gene ID: (Human) 23596
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