|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic non-phosphopeptide derived from human EPHB1/2/3/4 around the phosphorylation site of Tyr600/602/614/596 (F-T-YP-E-D)|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAPB; Developmental kinase 2; Developmental kinase 5; Developmentally-regulated Eph-related tyrosine kinase; EK2; EK5; EK6; ELK; ELK-related tyrosine kinase; Embryonic kinase 2; EPH tyrosine kinase 2; EPH tyrosine kinase 3; EPH-like kinase 2; EPH-like kinase 5; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPHB2, Ephrin type-B receptor 1; EPHB3, DRT; ephrin receptor EphB4; Ephrin type-B receptor 1; Ephrin type-B receptor 2; Ephrin type-B receptor 3; Ephrin type-B receptor 4; EPHT3; ERK; ETK2; HEK2; Hek5; Hepatoma transmembrane kinase; human embryo kinase 2; mDK-2; mDK-5; MGC87492; NET; NET, HEK-6, ELK, Ephrin type-B receptor 2, Ephrin type-B receptor 3, Ephrin B1, EphrinB1, EphrinB3, Ephrin B3, Ephrin B2, EphrinB2, Ephrin B4, EphrinB4, Ephrin type-B receptor 4; Neural kinase; Neuronally-expressed EPH-related tyrosine kinase; Nuk receptor tyrosine kinase; PCBC; protein-tyrosine kinase HEK5; Renal carcinoma antigen NY-REN-47; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyro5; TYRO6; Tyrosine kinase MYK-1; Tyrosine-protein kinase receptor EPH-2; Tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO11; Tyrosine-protein kinase TYRO5; Tyrosine-protein kinase TYRO6
Gene Aliases: 9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; CAPB; Cek10; Cek5; Cek6; DRT; EK2; EK5; ELK; Elkh; ENSMUSG00000074119; EPHB1; EPHB2; EPHB3; EPHB4; EPHT2; EPHT3; EPTH3; ERK; ETECK; ETK2; HEK2; HEK5; HEK6; HTK; MDK2; MDK5; MYK1; NET; Nuk; PCBC; Prkm5; Qek5; Sek3; Sek4; TYRO11; TYRO5; TYRO6
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.