|ELISA (ELISA)||5-10 µg/mL|
|Tested Species reactivity||Chemical|
|Host / Isotype||Sheep / IgG|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-75128 specifically detects Epiandrosterone.
PA1-75128 has been successfully used in ELISA applications.
The PA1-75128 immunogen is Epiandrosterone(17)-BTG.
Epiandrosterone is a dehydroepiandrosterone metabolite and a precursor of testosterone and estradiol with hypolipidemic and anabolic property. Epiandrosterone, a potential neurosteroid, appears to bind to the gamma-aminobutyric acid (GABA)/benzodiazepine-receptor complex (GABA-RC), acting as a negative non-competitive modulator of GABA-RC as well as signal through the N-methyl-D-aspartate receptor. In addition this agent inhibits the pentose phosphate pathway (PPP) thereby dilating blood vessels pre-contracted by partial depolarization. Also, epiandrosterone inhibits the synthesis of thromboxane A2 in activated platelets, reduces plasma plasminogen activator inhibitor type 1 and tissue plasminogen activator antigen, increases serum levels of insulin-like growth factor 1 and increases cyclic guanosine monophosphate and nitric oxide synthesis. These effects may improve circulation in the microvasculature. [National Center for Biotechnology Information. PubChem Compound Database; CID=441302]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3Beta-hydroxy-5alpha-androstan-17-one; C19H30O2; Isoandrosterone; Trans-Androsterone
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