|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human, Rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human ERR--alpha 1 (98-171 aa).|
|Purification||Ammonium sulfate precipitation|
|Storage buffer||physiological saline|
|Contains||0.1% sodium azide|
Estrogen-related receptor alpha (ERR alpha), a NR3 Steroid Receptor, was isolated based on sequence similarity in its DNA-binding domain to estrogen receptor alpha (ER alpha). ERR alpha has been shown to regulate the promoters of lactoferrin, medium-chain acyl CoA dehydrogenase, osteopontin, and thyroid receptor alpha, and it may affect cellular energy balance and bone formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ERR-alpha; ERR1; ESRL1; ESRRA; Estrogen receptor-like 1; estrogen-related nuclear receptor alpha; Estrogen-related receptor alpha; estrogen-related receptor, alpha; NR3B1; Nuclear receptor subfamily 3 group B member 1; orphan nuclear receptor; Steroid hormone receptor ERR1
Gene Aliases: ERR1; ERRa; ERRalpha; Errra; ESRL1; ESRRA; NR3B1
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