|Immunocytochemistry (ICC)||2 µg/mL|
|Immunofluorescence (IF)||2 µg/mL|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4 µg/ml|
|Western Blot (WB)||1-3 µg/mL|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Rat|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified rat liver estrogen sulfotransferase|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12775 targets Estrogen Sulfotransferase in IF and IHC (P) applications and shows reactivity with Rat samples.
The MA5-12775 immunogen is purified rat liver estrogen sulfotransferase.
Mammalian EST sulfurylates the hydroxyl group of estrogenic steroids by transferring the sulfate from a cosubstrate adenosine 3'-phosphate-5'-phosphosulfate. Sulfurylated steroids do not bind to the estrogen receptor with high affinity and, therefore, are hormonally inactive. EST plays an important role in controlling the intracellular level of the receptor-active estrogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EST-1; EST-3; estrogen sulfotransferase; estrogen sulfotransferase, isoform 1; estrogen sulfotransferase, isoform 3; estrogen-preferring; estrone sulfotransferase; sulfotransferase; sulfotransferase 1E1; sulfotransferase family 1E, member 1; sulfotransferase, estrogen preferring; sulfotransferase, estrogen-preferring
Gene Aliases: ESTSUL; ST1E1; Ste
Entrez Gene ID: (Rat) 25355
Molecular Function: transferase
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