|Immunohistochemistry (Paraffin) (IHC (P))||1:10|
|Miscellaneous PubMed (MISC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 3 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Hamster Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant oncoprotein corresponding to aa 226-454 of human Ets-1|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12375 targets Ets-1 in IHC (P) applications and shows reactivity with Human samples.
The MA5-12375 immunogen is recombinant oncoprotein corresponding to aa 226-454 of human Ets-1.
Ets-1 is a transcription factor involved in the regulation of genes required for extracellular matrix remodeling during metastasis of tumors. It is known to interact with the enhancer of urokinase like plasminogen activator, and promoters of stromelysin-1 and collagenase-1. It is absent from normal gastric mucosa but is expressed in 60% of gastric carcinoma and oral squamous cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; ets protein; p54; Protein C-ets-1; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1
Gene Aliases: c-ets-1; ETS-1; ETS1; EWSR2; p54
UniProt ID: (Human) P14921
Entrez Gene ID: (Human) 2113
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