|Immunohistochemistry (Paraffin) (IHC (P))||1:10|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant protein corresponding to C-terminal cytoplasmic domain of human EAAT2|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12360 targets Excitatory Amino Acid Transporter 2 in IHC (P) applications and shows reactivity with Human samples.
The MA5-12360 immunogen is recombinant protein corresponding to C-terminal cytoplasmic domain of human EAAT2.
Human excitatory amino acid transportes regulating neurotransmitter concentrations at the excitatory glutamatertic synapses of the mammalian central nervous system. They reduce extracellular glutamate concentration modulating synaptic signaling which helps reduce the risk of excitotoxicity. Expression of EATT2 is restricted to motor cortex area of the brain. EATT1 blocks the transport mediated by EATT2. EATT2 shares homology to L-glutamate transporter (GLT-1) from brain tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; Glutamate/aspartate transporter II; member 2; Sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1; solute carrier family 1 (glial high affinity glutamate transporter), member 2; Solute carrier family 1 member 2
Gene Aliases: EAAT2; GLT-1; GLT1; HBGT; SLC1A2
UniProt ID: (Human) B4DQE9
Entrez Gene ID: (Human) 6506
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