|Western Blot (WB)||1:1000|
|Tested Species reactivity||Bovine, Dog, Human, Mouse, Non-human primate, Rat, Xenopus|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the residues surrounding pThr567 of human ezrin|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with related proteins such as merlin or band 4.
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytovillin; cytovillin 2; epididymis secretory protein Li 105; Ezrin; p81; villin 2; villin 2 (ezrin); Villin-2
Gene Aliases: AW146364; BOS_138; CVIL; CVL; EZR; HEL-S-105; p81; R75297; VIL2
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