|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from 2nd extracellular domain of human F2RL1.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey (100%) Marmoset, Mouse, Rat, Hamster (94%) Gorilla, Horse, Pig (89%).
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coagulation factor II (thrombin) receptor-like 1; Coagulation factor II receptor-like 1; F2RL1; G-protein coupled receptor 11; GPR11; PAR-2; PAR2; Protease-activated receptor 2; Proteinase-activated receptor 2; Thrombin receptor-like 1
Gene Aliases: F2RL1; GPR11; PAR2
UniProt ID: (Human) P55085
Entrez Gene ID: (Human) 2150
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