|Western Blot (WB)||0.5-1.5 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ERLQALKTMKQH) corresponding to the C-terminus amino acids of ZMPSTE24|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAAX prenyl protease; CAAX prenyl protease 1 homolog; FACE-1; FACE1; Farnesylated proteins-converting enzyme 1; farnesylated-proteins converting enzyme 1; FLJ14968; MADB; Prenyl protein-specific endoprotease 1; STE24; Ste24p; zinc metallopeptidase (STE24 homolog, yeast); zinc metallopeptidase STE24 homolog; zinc metalloproteinase (STE24 homolog, yeast); Zinc metalloproteinase Ste24 homolog; zinc metalloproteinase, STE24 (yeast, homolog); ZMPSTE24
Gene Aliases: FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p; ZMPSTE24
UniProt ID: (Human) O75844
Entrez Gene ID: (Human) 10269
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