|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (DLTNKEGKKPEEK) corresponding to the internal amino acids of SUPT16H|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, mouse and porcine based on sequence homology.
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT , interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC68; Chromatin-specific transcription elongation factor 140 kDa subunit; chromatin-specific transcription elongation factor large subunit; facilitates chromatin remodeling 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; FACT; FACT 140 kDa subunit; FACT complex subunit SPT16; FACTP140; FLJ10857; FLJ14010; FLJ34357; HGNC:11465; hSPT16; SPT16/CDC68; suppressor of Ty 16 homolog; suppressor of Ty 16 homolog (S. cerevisiae); SUPT16H
Gene Aliases: CDC68; FACT140; FACTP140; SPT16; SPT16/CDC68; SUPT16H
UniProt ID: (Human) Q9Y5B9
Entrez Gene ID: (Human) 11198
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