|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 247 and 444 of Human FADS1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30080 targets FADS1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30080 immunogen is recombinant fragment corresponding to a region within amino acids 247 and 444 of Human FADS1.
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D5D; delta(5) desaturase; Delta(5) fatty acid desaturase; delta-5 desaturase; delta-5 fatty acid desaturase; FADS6; FADSD5; Fatty acid desaturase 1; linoleoyl-CoA desaturase (delta-6-desaturase)-like 1; LLCDL1; TU12
Gene Aliases: D5D; FADS1; FADS6; FADSD5; LLCDL1; TU12
UniProt ID: (Human) O60427
Entrez Gene ID: (Human) 3992
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