|Western Blot (WB)||1-2 ug/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 15 amino acid peptide near the carboxy terminus of human FAM212A|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is EL4 cell lysate.
PA5-20863 can be used with blocking peptide PEP-0977.
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives. FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics. In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C3orf54, INKA1; family with sequence similarity 212, member A; HInca; Induced in neural crest by AP2-alpha protein homolog; MInca; PAK4-inhibitor INKA1; protein FAM212A; uncharacterized protein C3orf54, INCA
Gene Aliases: 6230427J02Rik; C3orf54; FAM212A; INKA1
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