|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the C-terminal region of human FAM3D|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 50% glycerol, 150mM NaCl|
|Contains||0.02% sodium azide|
Members of the FAM3 family were identified based on structural, but not sequence, homology to short chain cytokines including IL-2, IL-4 and GM-CSF. FAM3 proteins are four helix bundle cytokines with four conserved cysteines in all members (FAM3A-D). FAM3B (also known as PANDER, for pancreatic derived factor) is highly expressed in alpha and beta cells of the pancreas and is being investigated as a potential contributor to beta cell death and development of type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytokine-like protein EF-7; EF7; family with sequence similarity 3, member D; OIT1; Protein FAM3D; Protein FAM3D precursor; UNQ567/PRO1130
Gene Aliases: EF7; FAM3D; OIT1; UNQ567/PRO1130
UniProt ID: (Human) Q96BQ1
Entrez Gene ID: (Human) 131177
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