|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 151 and 440 of Human FAM48A|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28049 targets FAM48A in WB applications and shows reactivity with Human samples.
The PA5-28049 immunogen is recombinant fragment corresponding to a region within amino acids 151 and 440 of Human FAM48A.
Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bA421P11.4; C13; C13orf19; family with sequence similarity 48, member A; p38 interacting protein; p38-interacting protein; P38IP; protein FAM48A; SPT20; suppressor of Ty 20 homolog; transcription factor (p38 interacting protein); Transcription factor SPT20 homolog; tumor rejection antigen
Gene Aliases: C13; C13orf19; FAM48A; FP757; P38IP; SPT20; SUPT20H
UniProt ID: (Human) Q8NEM7
Entrez Gene ID: (Human) 55578
Molecular Function: transcription factor
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