|Western Blot (WB)||1:500 - 1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic Peptide: L(70) Q L A R D R S A E G R A L Y A(85)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-4349 detects FBG4 from human, mouse and rat samples.
PA1-4349 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~31 kDa protein representing FBG4.
PA1-4349 immunizing peptide corresponds to amino acid residues 70-85 from human FBG4 protein.
Maintain antibody at 4°C for up to 3 months. Store at -20°C long term, avoiding freeze/thaw cycles.
F-box proteins, a critical component of the evolutionary conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a third subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: F Box Gama 4; F-box only protein 17; F-box only protein 26; F-box protein FBG4; FBXO17
Gene Aliases: FBG4; FBX17; FBX26; FBXO17; FBXO26
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