|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1274 and 1336 of Human FBXL10|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28141 targets FBXL10 in WB applications and shows reactivity with Human and mouse samples.
The PA5-28141 immunogen is synthetic peptide corresponding to a region within amino acids 1274 and 1336 of Human FBXL10.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: [Histone-H3]-lysine-36 demethylase 1B; CXXC-type zinc finger protein 2; CXXC2; EMSY-interactor; F-box and leucine-rich repeat protein 10; F-box protein containing leucine repeats 10; F-box protein FBL10; F-box/LRR-repeat protein 10; Fbl10; FBXL10; JEMMA (Jumonji domain; JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein; JHDM1B; jmjC domain-containing; JmjC domain-containing histone demethylation protein 1B; jumonji C domain-containing histone demethylase 1B; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; lysine (K)-specific demethylase 2B; Lysine-specific demethylase 2B; methyltransferase motif) protein; PCCX2; Protein JEMMA; Protein-containing CXXC domain 2
Gene Aliases: CXXC2; FBL10; FBXL10; JHDM1B; KDM2B; Kiaa3014; PCCX2
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