|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 194 and 387 of Human FBXO4|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30514 targets FBXO4 in IF and WB applications and shows reactivity with Human samples.
The PA5-30514 immunogen is recombinant fragment corresponding to a region within amino acids 194 and 387 of Human FBXO4.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants.
Protein Aliases: F-box only protein 4; F-box protein Fbx4; FBX4
Gene Aliases: FBX4; FBXO4
UniProt ID: (Human) Q9UKT5
Entrez Gene ID: (Human) 26272