|Western Blot (WB)||1-5 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli.|
|Storage buffer||PBS, pH 7.4|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-23228 detects FEN1 in Human samples.
MA1-23228 has been successfully used in Western Blot procedures.
MA1-23228 immunogen corresponds to Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli..
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 a protein that functions as an endonuclease that cleaves branched DNA structures containing single-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1 endonuclease and exonuclease activities are stimulated by an association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to have important roles in DNA replication and repair and is required in cell-free DNA replication systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNase IV; FEN-1; FEN1; Flap endonuclease 1; Flap structure-specific endonuclease 1; Maturation factor 1; maturation factor-1; MF1; RAD2
Gene Aliases: AW538437; FEN-1; FEN1; MF1; RAD2
UniProt ID: (Human) P39748
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