|Western Blot (WB)||0.01-0.03 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (QNKQKEQRELMKK) corresponding to the internal amino acids of FEZ1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, mouse and rat based on sequence homology.
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: fasciculation and elongation protein zeta 1 (zygin I); Fasciculation and elongation protein zeta-1; FEZ1; zygin 1; Zygin I; Zygin-1
Gene Aliases: FEZ1; UNC-76
UniProt ID: (Human) Q99689
Entrez Gene ID: (Human) 9638
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