|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide from internal region of human FGFR-2 protein|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is liver or breast carcinoma.
Fibroblast growth factors (FGFs) are members of a large family of structurally related polypeptides that are potent physiological regulators of growth and differentiantion for a wide variet of cells of mesodermal, ectodermal, and endodermal origin. Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR-1, FGFR-2, FGFR-3, and FGFR-4. FGFRs are members of the tyrosine kinase family of growth factor receptors. FGFR-2 is highly expressed in developing human tissues including the brain, choroids plexus, lung etc.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bacteria-expressed kinase; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF Receptor 2; FGFR-2; Fibroblast Growth Factor Receptor 2; JWS; K-SAM; Keratinocyte growth factor receptor; KGFR; protein tyrosine kinase, receptor like 14; TK14; TK25
Gene Aliases: BBDS; BEK; BFR-1; CD332; CEK3; CFD1; ECT1; FGFR2; JWS; K-SAM; KGFR; KSAM; TK14; TK25
UniProt ID: (Human) B4DFC2
Entrez Gene ID: (Human) 2263
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.