|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 28 and 286 of Human FGL1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30030 targets FGL1 in WB applications and shows reactivity with Human and mouse samples.
The PA5-30030 immunogen is recombinant fragment corresponding to a region within amino acids 28 and 286 of Human FGL1.
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: fibrinogen-like 1; Fibrinogen-like protein 1; fibrinogen-related protein 1; Hepassocin; hepatocellular carcinoma-related sequence; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; HFREP1; HP-041; LFIRE-1; LFIRE1; Liver fibrinogen-related protein 1; MFIRE-1; Mouse fibrinogen-related protein 1
Gene Aliases: FGL1; HFREP1; HP-041; LFIRE-1; LFIRE1; Mfire1
Molecular Function: signaling molecule
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