|ChIP assay (ChIP)||Assay-dependent|
|Immunohistochemistry (IHC)||3 µg/ml|
|Western Blot (WB)||0.5-1 µg/ml|
|Tested Species reactivity||Human, Mouse, Zebrafish|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (RTSGAFVYDCSKF) corresponding to the C-terminus amino acids of FOXC1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARA; congenital hydrocephalus; FKHL7; forkhead (Drosophila)-like 7; forkhead box C1; forkhead box C1 protein; Forkhead box protein C1; Forkhead, drosophila, homolog-like 7; forkhead-related activator 3; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; forkhead/winged helix-like transcription factor 7; FOXC1; FREAC-3; FREAC3; IGDA; IHG1; IRID1; iridogoniodysgenesis type 1; Mesoderm/mesenchyme forkhead 1; MF-1; myeloid factor-delta; RIEG3; Transcription factor FKH-1
Gene Aliases: ARA; ch; fkh-1; Fkh1; FKHL7; FOXC1; FREAC-3; FREAC3; frkhda; IGDA; IHG1; IRID1; Mf1; Mf4; RIEG3
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