|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 99-128 amino acids from the central region of human FRAT1|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FRAT-1; FRAT1; Frequently rearranged in advanced T-cell lymphomas; Frequently rearranged in advanced T-cell lymphomas 1; Proto-oncogene FRAT1
Gene Aliases: FRAT1
UniProt ID: (Human) Q92837
Entrez Gene ID: (Human) 10023
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