|Immunofluorescence (IF)||20 ug/mL|
|Western Blot (WB)||1 - 2 ug/mL|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 16 amino acid peptide near the carboxy terminus of human FRL1|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is EL4 cell lysate.
PA5-34477 can be used with blocking peptide PEP-1519.
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C17orf1; C17orf1B; CLL-associated antigen KW-13; FHOD4; FMNL; FMNL1; Formin-like 1; Formin-like protein 1; formin-related gene in leukocytes; Formin-related protein; FRL1; KW-13; Leukocyte formin; lymphocyte specific formin related protein
Gene Aliases: 8030453N10Rik; AI553564; C17orf1; C17orf1B; FHOD4; FMNL; FMNL1; Fnrl; Frl; FRL1; Frls; KW-13
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