|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 382 and 698 of Human FYB|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29331 targets FYB in WB applications and shows reactivity with Human samples.
The PA5-29331 immunogen is recombinant fragment corresponding to a region within amino acids 382 and 698 of Human FYB.
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADAP; Adhesion and degranulation promoting adaptor protein; adhesion and degranulation-promoting adaptor protein; FYB-120/130; FYN-binding protein; FYN-T-binding protein; p120/p130; PRO0823; SLAP-130; SLP-76-associated phosphoprotein
Gene Aliases: ADAP; FYB; PRO0823; SLAP-130; SLAP130
UniProt ID: (Human) O15117
Entrez Gene ID: (Human) 2533
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