|Immunohistochemistry (Paraffin) (IHC (P))||6 - 16 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 14 amino acid peptide from N-terminal extracellular domain of human FZD10 / Frizzled 10.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Monkey (100%) Gibbon, Hamster, Panda, Dog (93%) Marmoset, Mouse, Bovine, Horse, Pig (86%).
FZD10/Frizzled-10 is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family and containing a signal peptide, a cysteine-rich domain in the N-terminal, seven transmembrane domains and a C-terminal PDZ domain-binding motif. It is involved in transduction, intercellular transmission of polarity information during tissue morphogenesis in differentiated tissues and as a receptor for Wnt proteins. FZD10 is expressed highly in placenta, fetal kidney, fetal lung, brain cerebellum, cerebral cortex, medulla and spinal cord with very low levels in total brain, frontal lobe, temporal lobe, putamen, adult brain, heart, lung and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD350; CD350 antigen; Frizzled 10; frizzled 10, seven transmembrane spanning receptor; Frizzled family receptor 10; Frizzled homolog 10; Frizzled-10; FZ-10; Fz10; FZD10; FzE7; HFz10
Gene Aliases: CD350; FZ-10; Fz10; FZD10; FzE7; hFz10
UniProt ID: (Human) Q9ULW2
Entrez Gene ID: (Human) 11211
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