|Immunoprecipitation (IP)||2-10 µg|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant rat protein expressed in bacteria.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 15% glycerol|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Suggested positive control: IMR32 neuronal cell lysate, HEK 293 cell lysate, or brain lysate, antigen standard for APBB1 (transient overexpression lysate).
FE65 is a signaling adaptor of APP protein. The FE65/APP complex was shown to translocate into the cell nucleus and regulate gene expression. Genetic studies in mice validated FE65-APP interaction and molecular studies provided evidence on the role of the
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); Amyloid beta A4 precursor protein-binding family B member 1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein
Gene Aliases: APBB1; FE65; MGC:9072; RIR
Molecular Function: signaling molecule
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