|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 14 and 254 of Ferredoxin Reductase (Uniprot ID#P22570)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34833 targets Ferredoxin Reductase in WB applications and shows reactivity with Human samples.
The PA5-34833 immunogen is recombinant fragment corresponding to a region within amino acids 14 and 254 of Ferredoxin Reductase (Uniprot ID#P22570).
Ferredoxin reductase is a ubiquitous flavoenzyme, containing noncovalently bound FAD as a prosthetic group (1). It plays a role in delivering NADPH or low potential one-electron donors such as ferredoxin and flavodoxin to redox-based metabolisms in plastids, mitochondria and bacteria (2). In mammals, ferredoxin reductase is loosely associated with the inner mitochondrial membrane and receives electrons from NADPH. These electrons are transferred to ferredoxin which shuttles electrons to cytochrome P450 in the adrenal cortex mitochondrial steroid hydroxylation systems (3).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adrenodoxin reductase; adrenodoxin-NADP(+) reductase; ADXR; AR; ferredoxin NADP reductase; Ferredoxin reductase; Ferredoxin--NADP(+) reductase; mitochondrial; NADPH adrenodoxin oxidoreductase; NADPH:adrenodoxin oxidoreductase, mitochondrial
Gene Aliases: ADXR; FDXR
UniProt ID: (Human) P22570
Entrez Gene ID: (Human) 2232
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