|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 183 of Human Ferritin Heavy Chain|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27500 targets Ferritin Heavy Chain in WB applications and shows reactivity with Human samples.
The PA5-27500 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 183 of Human Ferritin Heavy Chain.
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoferritin; Cell proliferation-inducing gene 15 protein; Ferritin H subunit; Ferritin heavy chain; ferritin, heavy polypeptide 1; FHC; FTH; FTHL6; PIG15; placenta immunoregulatory factor; PLIF; proliferation-inducing protein 15
Gene Aliases: FHC; FTH; FTH1; FTHL6; HFE5; OK/SW-cl.84; PIG15; PLIF
UniProt ID: (Human) P02794
Entrez Gene ID: (Human) 2495
Molecular Function: storage protein
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