|ELISA (ELISA)||Assay dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay dependent|
|Western Blot (WB)||1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Fibrinogen protein purified from human plasma.|
|Storage buffer||HEPES with 0.15M NaCl, 0.01% BSA, 50% glycerol|
|Contains||0.03% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
A suggested positive control for this product is human plasma.
Fibrinogen is a soluble glycoprotein found in the plasma, with a molecular weight of 340kDa. It comprises of three pairs of non-identical polypeptide chains (alpha, 63.5kDa beta, 56kDa, and gamma, 47kDa chains) linked to each other by disulphide bonds. Low plasma fibrinogen concentrations are therefore associated with an increased risk of bleeding due to impaired primary and secondary hemostasis. Therefore Fibrinogen is an essential component of the blood coagulation system. Also it may play key roles in the process of atherosclerotic lesion formation, with subsequent effects on cardiovascular diseases. And increasing evidence from epidemiological studies suggests that elevated plasma fibrinogen levels are associated with an increased risk of ischaemicheart disease (IHD), stroke and other thromboembolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FGA; Fib2; Fibrinogen A alpha polypeptide chain; Fibrinogen alpha chain; fibrinogen, A alpha polypeptide
Gene Aliases: FGA; Fib2
UniProt ID: (Human) P02671
Entrez Gene ID: (Human) 2243
Molecular Function: signaling molecule
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