|Flow Cytometry (Flow)||1:20|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Fibrinogen isolated from human serum|
|Storage buffer||TBS, pH 7.4, with 1% carrier protein|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, store in dark, DO NOT FREEZE!|
PA5-16599 targets Fibrinogen in IF applications and shows reactivity with Human samples.
The PA5-16599 immunogen is fibrinogen isolated from human serum.
The protein encoded by this gene is the alpha component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in two isoforms which vary in the carboxy-terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A alpha polypeptide; fibrinogen; Fibrinogen alpha chain; fibrinogen, A alpha polypeptide
Gene Aliases: FGA; Fib2
UniProt ID: (Human) P02671
Entrez Gene ID: (Human) 2243
Molecular Function: signaling molecule
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