|Western Blot (WB)||1:200-1:2000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Sheep|
|Immunogen||A synthetic peptide from aa region 10-50 of human GABA(A) conjugated to an immunogenic carrier protein has been used as the antigen|
|Storage buffer||whole serum|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Reconstitute with 150 ul of distilled water.
Centrifuge to remove any insoluble material.
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATG8; FLC3A; GABA(A) receptor-associated protein like 2; GABA(A) receptor-associated protein-; GABA(A) receptor-associated protein-like 2; GABARAPL2; gamma-aminobutyric acid (GABA-A) receptor-associated protein-like 2; Gamma-aminobutyric acid receptor-associated protein-like 2; Ganglioside expression factor 2; GATE-16; GATE16; GEF-2; GEF2; General protein transport factor p16; Golgi-associated ATPase enhancer of 16 kDa; MAP1 light chain 3 related protein; MAP1 light chain 3-related protein
Gene Aliases: 0610012F20Rik; 2900019O08Rik; AI173605; ATG8; ATG8C; FLC3A; GABARAPL2; GATE-16; GATE16; GEF-2; GEF2
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