|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 225 of Human GBAS|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-32157 targets GBAS in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-32157 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 225 of Human GBAS.
Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor.The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 2; Glioblastoma-amplified sequence; NIPSNAP2; Protein NipSnap homolog 2
Gene Aliases: AV006093; GBAS; NIPSNAP2
UniProt ID: (Human) O75323
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