|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 13-41 amino acids from the N-terminal region of human GDF5|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BMP-14; Bone morphogenetic protein 14; Cartilage-derived morphogenetic protein 1; cartilage-derived morphogenetic protein-1; CDMP-1; GDF-5; Growth/differentiation factor 5; LAP-4; Lipopolysaccharide-associated protein 4; LPS-associated protein 4; Radotermin
Gene Aliases: BDA1C; BMP-14; BMP14; CDMP1; GDF5; LAP-4; LAP4; OS5; SYM1B; SYNS2
UniProt ID: (Human) P43026
Entrez Gene ID: (Human) 8200
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