|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1-3 µg/mL|
|Western Blot (WB)||See 5 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A 20 amino acid synthetic peptide derived from bovine brain Rab Guanine Nucleotide Dissociation Inhibitor (GDI).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1A; alpha; GDI-1; GDIL; GDP-dissociation inhibitor 1; Guanosine diphosphate dissociation inhibitor 1; mental retardation; mental retardation, X-linked 48; MRX41; MRX48; Oligophrenin-2; OPHN2; Protein XAP-4; Rab GDI alpha; Rab GDIalpha; Rab GDP dissociation inhibitor alpha; rab GDP-dissociation inhibitor; rab GDP-dissociation inhibitor, alpha; RABGD1A; RABGDIA; testis secretory sperm-binding protein Li 208a; X-linked 48; XAP-4
Gene Aliases: 1A; GDI1; GDIA; GDIalpha; GDIL; MRX41; MRX48; OPHN2; RABGD1A; RABGDIA; XAP-4; XAP4
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