|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 105 and 300 of Human GGPS1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28470 targets GGPS1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28470 immunogen is recombinant fragment corresponding to a region within amino acids 105 and 300 of Human GGPS1.
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (2E; (2E,6E)-farnesyl diphosphate synthase; 6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyltranstransferase; Geranylgeranyl diphosphate synthase; Geranylgeranyl pyrophosphate synthase; Geranyltranstransferase; GGPP synthase; GGPPS; GGPPS1; GGPPSase
Gene Aliases: GGPPS; GGPPS1; GGPS1
UniProt ID: (Human) O95749
Entrez Gene ID: (Human) 9453
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