|Western Blot (WB)||0.01-0.03 ug/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (YLLIRYCSGKSKKP) corresponding to the C-terminus amino acids of GJB2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with human and rat based on sequence homology.
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Connexin 26; Connexin-26; CX26; DFNA3; DFNB1; Gap junction beta-2 protein; gap junction membrane channel protein beta 2; gap junction protein beta 2; gap junction protein, beta 2, 26kD (connexin 26); gap junction protein, beta 2, 26kDa (connexin 26); GJB2; HID; KID; NSRD1; PPK
Gene Aliases: AI325222; Cnx26; Cx26; Cxn-26; Gjb-2; Gjb2
UniProt ID: (Mouse) Q00977
Entrez Gene ID: (Mouse) 14619
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