|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||0.5-1 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (101 PENTHILDGNAVDLQAEC 118) of GNPDA1 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
GNPDA1 is an allosteric enzyme catalyzing the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium, a reaction that under physiological conditions proceeds to the formation of fructose-6-phosphate. It is the sole enzyme linking hexosamine systems with glycolytic pathways by transferring hexosamines from structural macromolecules into the glycolytic pathway. GNPDA1 localizes close to the developing acrosome vesicle and in spermatozoa close to the acrosomal region, and may play a role in the acrosome reaction. Human GNPDA1 gene is localized to chromosome 5q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glcN6P deaminase 1; Glucosamine-6-phosphate deaminase 1; Glucosamine-6-phosphate isomerase 1; glucose-6-phosphate isomerase; GNP1; GNPDA 1; GNPI; HLN; Oscillin
Gene Aliases: GNP1; GNPDA; GNPDA1; GNPI; GPI; HLN; KIAA0060; oscillin
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