|Flow Cytometry (Flow)||20 ul/10^6 cells|
|Tested Species reactivity||Human, Non-human primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Peripheral blood mononuclear cells of a patient suffering with CLL.|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C, store in dark, DO NOT FREEZE!|
CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Antigen CD42b-alpha; BSS; CD42B; CD42b-alpha; glycoprotein Ib (platelet), alpha polypeptide; GP-Ib alpha; GP1B; GPIB; MGC34595; mutant platelet membrane glycoprotein Ib-alpha; Platelet glycoprotein Ib alpha chain; platelet membrane glycoprotein 1b-alpha subunit; platelet membrane glycoprotein Ib-alpha
Gene Aliases: BDPLT1; BDPLT3; BSS; CD42B; CD42b-alpha; DBPLT3; GP1B; GP1BA; GPIbA; GPIbalpha; VWDP
UniProt ID: (Human) P07359
Entrez Gene ID: (Human) 2811
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.