|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||3 - 4 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GPR109B / HM74.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
BLAST analysis of the peptide immunogen showed 100% homology with human protein HCAR2.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Panda (89%).
This is a receptor for nicotinic acid. Its expression has been reported in adipose and spleen, as well as lymphocytes and monocytes. ESTs have been isolated from adipose, blood, liver, liver/spleen, placenta, prostate, and testis libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 109B; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GPR109B; GTP-binding protein; HCA3; HCAR3; HM74; HM74b; hydroxy-carboxylic acid receptor 3; Hydroxycarboxylic acid receptor 3; Niacin receptor 2; NIACR2; Nicotinic acid receptor 2; Puma-g; PUMAG; Putative chemokine receptor
Gene Aliases: GPR109B; HCA3; HCAR3; HM74; HM74B; NIACR2; Puma-g; PUMAG
UniProt ID: (Human) P49019
Entrez Gene ID: (Human) 8843
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.