|Immunohistochemistry (Paraffin) (IHC (P))||11 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 20 amino acid peptide from N-terminal extracellular domain of human GPR124.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
In IHC applications, antigen retrieval using a citrate buffer (pH 6.0) is recommended.
Percent identity with other species by BLAST analysis: Human, Gorilla (100%) Gibbon, Monkey (90%) Dog (85%).
Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2. ESTs have been isolated primarily from amnion, connective tissue, ear, embryo, eye, ganglion, heart, lung, placenta, and skin libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adhesion G protein-coupled receptor A2; G protein-coupled receptor 124; G-protein coupled receptor 124; TEM5; Tumor endothelial marker 5
Gene Aliases: ADGRA2; GPR124; KIAA1531; TEM5
UniProt ID: (Human) Q96PE1
Entrez Gene ID: (Human) 25960
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