|Immunohistochemistry (Paraffin) (IHC (P))||1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated Cys-SSSKIPFRSRSPSDV|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
IHC (P) analysis shows positive staining of GPR3 in human pancreatic duct tissue.
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600-1,000 members and is the largest known class of molecular targets with proven therapeutic value. GPR3 is an orphan receptor with constitutive G signaling activity. GPR3 modulates a number of brain functions, including behavioral responses to stress, neurite outgrowth and amyloid-beta peptide generation suggesting that it may play a role in Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACCA; ACCA orphan receptor; Adenylate Cyclase Constitutive Activator; G protein-coupled receptor 3; G-protein coupled receptor 3; GPR3
Gene Aliases: ACCA; GPR3
UniProt ID: (Human) P46089
Entrez Gene ID: (Human) 2827
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