|Immunohistochemistry (Frozen) (IHC (F))||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||1.0-2.0 µg/ml|
|Tested Species reactivity||Human, Pig|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal portion of the human GPR49/LGR5 protein (within residues 650-700).|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody is not recommended for Immunocytochemistry/Immunofluorescence.
GPR49/LGR5 is an orphaned member of the glycoprotein hormone receptor subfamily. It is thought to play an important role in growth and differentiation of embyronic tissue. It is highly expressed in the brain, spinal cord, placenta, and skeletal muscle. GPR49/LGR5 is up-regulated in several cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FEX; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; GPR49; GPR67; GRP49; HG38; leucine-rich repeat containing G protein-coupled receptor 5; leucine-rich repeat-containing G protein-coupled receptor 5; Leucine-rich repeat-containing G-protein coupled receptor 5; orphan G protein-coupled receptor HG38
Gene Aliases: FEX; GPR49; GPR67; GRP49; HG38; LGR5
UniProt ID: (Human) O75473
Entrez Gene ID: (Human) 8549
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