|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 129 and 221 of GPR54|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 50% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27179 targets GPR54 in WB applications and shows reactivity with Human samples.
The PA5-27179 immunogen is a synthetic peptide corresponding to a region within amino acids 129 and 221 of GPR54.
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AXOR12; G protein-coupled receptor 54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; GPR54; HOT7T175; Hypogonadotropin-1; KiSS-1 receptor; KiSS-1R; Kisspeptins receptor; Metastin receptor
Gene Aliases: AXOR12; CPPB1; GPR54; HH8; HOT7T175; KISS-1R; KISS1R
UniProt ID: (Human) Q969F8
Entrez Gene ID: (Human) 84634
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