|Immunohistochemistry (Paraffin) (IHC (P))||9 - 18 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 13 amino acid peptide from 3rd extracellular domain of human GPR83.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Bovine, Horse, Rabbit, Pig (100%) Elephant, Panda, Bat, Dog (92%).
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G protein-coupled receptor 72; G protein-coupled receptor 83; G-protein coupled receptor 72; GIR; glucocorticoid induced receptor; GPR72; GPR83; Hcepto9; Jp05; KIAA1540; Probable G-protein coupled receptor 83
Gene Aliases: GIR; GPR72; GPR83; KIAA1540
UniProt ID: (Human) Q9NYM4
Entrez Gene ID: (Human) 10888
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