|Western Blot (WB)||1-3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (ELDLSPPHLSSSPE) corresponding to the N-terminus amino acids of GRB7|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase . Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B47; Epidermal growth factor receptor GRB-7; GRB7; GRB7 adapter protein; Growth factor receptor-bound protein 7; OTTHUMP00000164352
Gene Aliases: GRB7
UniProt ID: (Human) Q14451
Entrez Gene ID: (Human) 2886
Molecular Function: transmembrane receptor regulatory/adaptor protein
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