|Western Blot (WB)||0.3-1 ug/ml|
|Tested Species reactivity||Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KIRQLPIDSDDSRP) corresponding to the internal amino acids of GRIK3|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and human based on sequence homology.
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members . A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); excitatory amino acid receptor 5; GLR7; GluK3; GluR-7; GLUR7; GluR7a; Glutamate receptor 7; Glutamate receptor ionotropic, kainate 3; glutamate receptor subunit kainate subtype; glutamate receptor, ionotropic, kainate 3; GRIK3
Gene Aliases: 9630027E11; GluK3; Glur-7; GluR7; GluR7-3; Grik3
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