|Western Blot (WB)||1 - 2 ug/mL|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||An 18 amino acid peptide near the center of human GRINA|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
A suggested positive control is human testis tissue lysate.
PA5-34489 can be used with blocking peptide PEP-1531.
The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glutamate [NMDA] receptor-associated protein 1; Glutamate receptor ionotropic N-methyl D-aspartate-associated protein 1; glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); glutamate receptor, NMDA subtype, glutamate-binding subunit; GRINA; HNRGW; LFG1; NMDA receptor glutamate-binding subunit; NMDARA1; Protein lifeguard 1; Putative MAPK-activating protein PM02; TMBIM3; transmembrane BAX inhibitor motif containing 3; Transmembrane BAX inhibitor motif-containing protein 3
Gene Aliases: GRINA; HNRGW; LFG1; NMDARA1; TMBIM3
UniProt ID: (Human) Q7Z429
Entrez Gene ID: (Human) 2907
Molecular Function: receptor
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