|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 633-660 amino acids from the C-terminal region of human AD_K2|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adrenergic, beta, receptor kinase 2; beta ARK2; Beta-adrenergic receptor kinase 2; Beta-ARK-2; G-protein coupled receptor kinase 3; G-protein-coupled receptor kinase 3
Gene Aliases: 4833444A01Rik; Adrbk-2; ADRBK2; AI851927; AW551196; Bark-2; BARK2; GRK3
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